Nonfunctioning giant pituitary adenomas: Invasiveness and recurrence
نویسندگان
چکیده
منابع مشابه
Nonfunctioning giant pituitary adenomas: Invasiveness and recurrence
BACKGROUND We report our surgical series of 35 patients with giant nonfunctioning pituitary adenomas (GNFPA). We analyzed the rule of Ki-67 antigen expression in predicting recurrence. METHODS Thirty-five patients were operated between 2000 and 2010. Suprassellar extension of the tumors were classified according to Hardy and Mohr based on magnetic resonance (MR) studies. Pituitary endocrine f...
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CONTEXT GH replacement therapy (GH-RT) is a widely accepted treatment in GH-deficient adults with nonfunctioning pituitary adenoma (NFPAs). However, some concerns have been raised about the safety of GH-RT because of its potentially stimulating effect on tumor growth. OBJECTIVE The aim of this study was to evaluate tumor progression in NFPA patients using GH-RT. DESIGN, SETTING, AND PATIENT...
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OBJECTIVE Clinically nonfunctioning pituitary adenoma (NFPA) remains the only pituitary tumor subtype for which no effective medical therapy is available or recommended. We evaluated dopamine agonist (DA) therapy for preventing growth of postsurgical pituitary tumor remnants. DESIGN The study design included historical cohort analysis of clinical results at two pituitary referral centers with...
متن کاملSurgical treatment of giant pituitary adenomas.
Multidirectional extension and invasive spread are important features of giant pituitary adenomas. Operability cannot be established merely by determining the size of the most prominent part of the tumour. Detailed radiological evaluation with plain films, computed tomography, angiography, and air studies all contribute to evaluation of the precise anatomy before surgery. In the final decision ...
متن کاملSerum Levels of Fsh and Tsh in Nonfunctioning Pituitary Adenomas before and after Surgery
Clinically nonfunctioning human pituitary adenomas (NFPAs) constitute about 25-35% of pituitary tumours. Relatively few studies have been carried out to determine the cellular origin and biology of the NFPAs. The present study was undertaken to assess the effect of surgical removal of adenoma on peripheral adenohypophyseal hormones. In addition, the pituitary hormones have also been measured di...
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ژورنال
عنوان ژورنال: Surgical Neurology International
سال: 2015
ISSN: 2152-7806
DOI: 10.4103/2152-7806.170536